HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Pituitary cretinism in two sisters.

Abstract
Two sisters with cretinism are reported. Each showed low levels of serum triiodothyronine, thyroxine, and thyroid-stimulating hormone (TSH). In the elder sister, serum TSH did not increase after administration of thyrotropin-releasing hormone. We conclude that cretinism in these 2 sisters was due to TSH deficiency. This is the second report of 'familial' pituitary cretinism (TSH-deficient congenital hypothyroidism).
AuthorsH Kohno, N Watanabe, M Ootsuka, M Kajiwara, N Gohya
JournalArchives of disease in childhood (Arch Dis Child) Vol. 55 Issue 9 Pg. 725-7 (Sep 1980) ISSN: 1468-2044 [Electronic] England
PMID7436542 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Thyrotropin
Topics
  • Congenital Hypothyroidism (genetics)
  • Female
  • Humans
  • Infant
  • Pedigree
  • Thyrotropin (deficiency)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: