Abstract |
Two sisters with cretinism are reported. Each showed low levels of serum triiodothyronine, thyroxine, and thyroid-stimulating hormone (TSH). In the elder sister, serum TSH did not increase after administration of thyrotropin-releasing hormone. We conclude that cretinism in these 2 sisters was due to TSH deficiency. This is the second report of 'familial' pituitary cretinism (TSH-deficient congenital hypothyroidism).
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Authors | H Kohno, N Watanabe, M Ootsuka, M Kajiwara, N Gohya |
Journal | Archives of disease in childhood
(Arch Dis Child)
Vol. 55
Issue 9
Pg. 725-7
(Sep 1980)
ISSN: 1468-2044 [Electronic] England |
PMID | 7436542
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Congenital Hypothyroidism
(genetics)
- Female
- Humans
- Infant
- Pedigree
- Thyrotropin
(deficiency)
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