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A study of the treatment time necessary for the vasodilator drug isoxsuprine to prevent necrosis in a skin flap.

Abstract
These results show that administration of isoxsuprine at least 13 days prior to flap elevation and continuance at least 7 days postoperatively does lead to completre survival of the abdominal neurovascular island skin flap in the rat.
AuthorsB Zide, H J Buncke, F Finseth
JournalBritish journal of plastic surgery (Br J Plast Surg) Vol. 33 Issue 3 Pg. 383-7 (Jul 1980) ISSN: 0007-1226 [Print] England
PMID7426818 (Publication Type: Journal Article)
Chemical References
  • Isoxsuprine
Topics
  • Animals
  • Drug Administration Schedule
  • Graft Survival (drug effects)
  • Isoxsuprine (administration & dosage, therapeutic use)
  • Necrosis
  • Postoperative Complications (pathology, prevention & control)
  • Rats
  • Skin (pathology)
  • Surgical Flaps
  • Time Factors

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