[Preventive effect of several antibiotics in experimental rickettsial infections].

Abstract

Dibiomycin, biomycin, and biomycin in combination with erythromycin (antibiotics with a wide range of action) used once or in interrupted courses produced a distinct prophylactic effect in experimental rickettsia infection in guinea pigs. The most pronounced prophylactic action was observed when chemoprophylaxis was combined with immunization with inactivated typhud vaccine. Formation of typhus immunity was seen when such chemoprophylaxis scheme was followed.

• Authors: N D Klimchuk
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 8 Pg. 30-5 (Aug 1978) ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Izuchenie profilakticheskogo deĭstviia nekotorykh antibiotikov pri éksperimental'noĭ rikketsioznoĭ infektsii.
• PMID: 742277 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial
• Bacterial Vaccines
• Erythromycin
• Chlortetracycline

Topics

• Agglutination Tests
• Animals
• Antibodies, Bacterial (biosynthesis)
• Bacterial Vaccines (administration & dosage)
• Chlortetracycline (administration & dosage)
• Complement Fixation Tests
• Erythromycin (administration & dosage)
• Guinea Pigs
• Typhus, Epidemic Louse-Borne (prevention & control)
• Vaccination