Abstract |
Ten patients with generalized psoriasis, which included nail involvement, were treated with total-body oral photochemotherapy. A combination of methoxsalen and high-intensity ultraviolet A radiation was employed and its therapeutic efficacy in nail psoriasis ascertained. Among the ten patients, there were 26 instances of the following nail signs: pitting, onycholysis, "oil drop" change, subungual hyperkeratosis, nail-plate crumbling, proximal nail-fold psoriasis, and onychorrhexis. Of the 26, eighteen improved by 50% or more. Only pitting failed to respond to therapy in all of the eight patients who had this change.
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Authors | J L Marx, R K Scher |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 116
Issue 9
Pg. 1023-24
(Sep 1980)
ISSN: 0003-987X [Print] United States |
PMID | 7416754
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Humans
- Methoxsalen
(administration & dosage, therapeutic use)
- Nail Diseases
(drug therapy)
- Photochemotherapy
- Psoriasis
(drug therapy)
- Ultraviolet Rays
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