[Effect of diazane on the mitotic cycle of transplantable leukemia LA in mice].

Abstract

Diazane inhibited for 25 hours the division of cells being at S-phase during its administration. The renewal of cell division was followed by their selective death. The substance failed to affect cells being at G2-phase of at termination of S-phase during its administration.

• Authors: S A Goncharova, N P Konovalova, V N Shevtsova
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 26 Issue 6 Pg. 59-63 ( 1980) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Vliianie diazana na kletochnyĭ tsikl perevivaemogo leĭkoza LA mysheĭ.
• PMID: 7385731 (Publication Type: English Abstract, Journal Article)

Chemical References

• Azo Compounds
• DNA, Neoplasm
• Diazonium Compounds
• Succinates
• diazan

Topics

• Animals
• Azo Compounds (pharmacology)
• Cell Cycle (drug effects)
• DNA, Neoplasm (biosynthesis)
• Depression, Chemical
• Diazonium Compounds
• Leukemia L1210 (drug therapy, metabolism)
• Mice
• Mitosis (drug effects)
• Succinates (pharmacology)