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Dissolution of gallstones in hamsters by 3-hydroxy-3-methylglutaric acid.

Abstract
Addition of 0.05--0.20% of 3-hydroxy-3-methylglutaric acid to a lithogenic hamster diet resulted in a marked reduction in the incidence of gallstones in hamsters.
AuthorsD Kritchevsky, J A Story, D M Klurfeld
JournalExperientia (Experientia) Vol. 34 Issue 10 Pg. 1328 (Oct 15 1978) ISSN: 0014-4754 [Print] Switzerland
PMID738409 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Glutarates
  • Hydroxy Acids
  • Chenodeoxycholic Acid
Topics
  • Animals
  • Chenodeoxycholic Acid (therapeutic use)
  • Cholelithiasis (etiology, prevention & control)
  • Cricetinae
  • Glutarates (therapeutic use)
  • Hydroxy Acids (therapeutic use)

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