[Quantitative evaluation of the efficacy of pharmacological agents in adrenaline-induced heart injury].

Abstract

It has been established that the protective or adrenaline heart injury enhancing effect of pharmacological agents manifests by regular shortening or prolongation of the time required for eosinophilia appearance as compared with the time it appears during administration of adrenalipe alone. This regularity lies at the basis of the quantitative evaluation of the efficacy of pharmacological agents in heart injury.

• Authors: V V Malyshev, O M Andreev
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 89 Issue 1 Pg. 23-5 ( 1980) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Kolichestvennaia otsenka effektivnosti farmakologicheskikh veshchestv pri povrezhdenii serdtsa adrenalinom.
• PMID: 7378563 (Publication Type: English Abstract, Journal Article)

Chemical References

• Hydrocarbons, Chlorinated
• Propranolol
• Aldrin
• Epinephrine

Topics

• Aldrin
• Animals
• Epinephrine
• Heart Diseases (chemically induced, physiopathology)
• Hydrocarbons, Chlorinated (pharmacology)
• Male
• Myocardium (pathology)
• Propranolol (pharmacology)
• Rats