[Morphological changes in the kidneys after carbon tetrachloride poisoning].

Structural alterations in the kidneys of 40 patients deceased from carbon tetrachloride (CCl4) poisoning were examined. All the patients had died with severe acute hepatic and renal failure. The authors found that it was consecutively developing hydropic and protein dystrophy of both proximal and distal tubules which accounted for acute renal failure. Changes in the glomeruli of the type of membranous glomerulopathy were also found. In the authors' opinion, the main cause of these alterations of the kidneys was presumably severe hepatic insufficiency with metabolic and immune disturbances.
AuthorsL N Zimina, L S Aganova
JournalArkhiv patologii (Arkh Patol) Vol. 42 Issue 3 Pg. 15-21 ( 1980) ISSN: 0004-1955 [Print] USSR
Vernacular TitleMorfologicheskie izmeneniia pochek pri otravlenii chetyrekhkhloristym uglerodom.
PMID7377996 (Publication Type: English Abstract, Journal Article)
  • Adult
  • Carbon Tetrachloride Poisoning (pathology)
  • Female
  • Humans
  • Kidney (drug effects, ultrastructure)
  • Kidney Glomerulus (ultrastructure)
  • Kidney Tubules, Distal (ultrastructure)
  • Kidney Tubules, Proximal (ultrastructure)
  • Male
  • Microscopy, Electron
  • Middle Aged

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