Preliminary results on the action of dihydroxydibutylether on the lithogenic index of patients with calculosis of the gall-bladder.

Abstract	Oral administration of 900 mg daily of dihydroxydibutylether to patients with cholesterol stones in the gall-bladder, reduced the lithogenic index of the bile, whose mean value shifted from 1.64 to 1.03 (p less than 0.01) after 20 days of treatment. Reduction of lithogenic index must be ascribed exclusively to the reduced biliary concentration of cholesterol.
Authors	G Missale, E Camarri, F Fici, A Agosti, M Mordini
Journal	International journal of clinical pharmacology, therapy, and toxicology (Int J Clin Pharmacol Ther Toxicol) Vol. 18 Issue 1 Pg. 42-3 (Jan 1980) ISSN: 0174-4879 [Print] Germany
PMID	7364531 (Publication Type: Journal Article)
Chemical References	Bile Acids and Salts Butanols Cholagogues and Choleretics Ethers Phospholipids Cholesterol 4,4'-oxydi-2-butanol
Topics	Adult Aged Bile (analysis) Bile Acids and Salts (analysis) Butanols (therapeutic use) Cholagogues and Choleretics (therapeutic use) Cholelithiasis (drug therapy, metabolism) Cholesterol (analysis) Ethers (therapeutic use) Female Humans Lipid Metabolism Middle Aged Phospholipids (analysis)

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