Abstract |
Twenty-three hospital in-patients with severe lower respiratory tract infections were treated with cefuroxime sodium. The drug was given intramuscularly in a dose of either 750 mg or 1000 mg at 8-hourly intervals for 5 days. Of the 21 patients who could be assessed, the response to treatment was highly satisfactory and there were no treatment failures. Eight patients had failed to respond to a course of oral antibiotics before being seen. Most of the patients were elderly and all were very ill. The sputum became mucoid in all but 1 patient. There was no change in tests of liver or renal function. Cefuroxime appears to be an effective and well-tolerated drug for the treatment of patients with severe chest infections.
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Authors | T C Samanta, R P Bax, R M Pearson, C W Havard, W Brumfitt, J M Hamilton-Miller |
Journal | Current medical research and opinion
(Curr Med Res Opin)
Vol. 6
Issue 7
Pg. 466-71
( 1980)
ISSN: 0300-7995 [Print] England |
PMID | 7363646
(Publication Type: Journal Article)
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Chemical References |
- Cephalosporins
- Cefuroxime
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Topics |
- Adult
- Aged
- Cefuroxime
(administration & dosage, metabolism, therapeutic use)
- Cephalosporins
(therapeutic use)
- Female
- Humans
- Injections, Intramuscular
- Male
- Middle Aged
- Respiratory Tract Infections
(blood, drug therapy, metabolism)
- Sputum
(metabolism)
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