Pathologic flail chest complicating multiple myeloma.

Abstract

Pathologic flail chest complicated the initial presentation of multiple myeloma in two patients. Both had severe hypercalcemia and diffuse bone disease. Atelectasis and pulmonary edema preceded the appearance of flail chest in one patient; atelectasis complicated the flail chest in the second patient and increased the severity of the flail. Both were treated with radiotherapy and chemotherapy. However, delay in stabilizing the first patient's chest wall with positive airway pressure was followed by extension of the flail chest and irreversible respiratory failure. On the other hand, prolonged stabilization of the chest wall in the second patient until a chemotherapy-induced remission occurred was associated with resolution of the flail chest.

• Authors: B Fleegler, C Fogarty, G Owens, E Cohen, P A Cassileth
• Journal: Archives of internal medicine (Arch Intern Med) Vol. 140 Issue 3 Pg. 414-5 (Mar 1980) ISSN: 0003-9926 [Print] United States
• PMID: 7362361 (Publication Type: Case Reports, Journal Article)

Topics

• Bone Neoplasms (complications)
• Female
• Flail Chest (etiology)
• Fractures, Spontaneous
• Humans
• Hypercalcemia (etiology)
• Lung Diseases (etiology)
• Male
• Middle Aged
• Multiple Myeloma (complications)
• Pulmonary Atelectasis (etiology)
• Pulmonary Edema (etiology)
• Respiratory Insufficiency (etiology)
• Rib Fractures (etiology)
• Sternum
• Thoracic Injuries (etiology)