[Drug-induced readjustment of therapy-resistant hypertension].

Abstract

By a combined vasodilator-[diisopropylamine (disostat), dihydralazine (depressan)] furosemide- (furesis-) infusion therapy was tried to achieve a new stabilisation of the blood pressure of therapy-refractory patients with hypertension. Propranolol (Obsidan) was additionally administered for the suppression of a sympathetic counter-regulation. On 3 patients is demonstrated how by a ten days' intensive decrease of the blood pressure and decrease of the extracellular fluid volume the therapy resistance may be interrupted and a repeated response to an oral antihypertensive standard therapy may be achieved.

• Authors: R Kiesewetter, R Herrmann
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 33 Issue 21 Pg. 793-5 (Nov 01 1978) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Pharmakainduzierte Neueinstellung der therapieresistenten Hypertonie.
• PMID: 735253 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Propylamines
• Furosemide
• Propranolol
• Dihydralazine

Topics

• Dihydralazine (therapeutic use)
• Drug Combinations
• Drug Resistance
• Furosemide (therapeutic use)
• Humans
• Hypertension (drug therapy)
• Male
• Middle Aged
• Propranolol (therapeutic use)
• Propylamines (therapeutic use)