Renovascular hypertension: treatment by percutaneous transluminal dilatation.

Abstract

Eight patients with unilateral renovascular hypertension underwent percutaneous transluminal dilatation. In seven, renal-artery stenoses were caused by atherosclerotic lesions and in one, by fibromuscular hyperplasia. After a 6-month follow-up period, three patients were cured of hypertension anf four showed improvement. Only one patient failed to respond: Failure was caused by an occluded left renal artery 3 months after the procedure. Renal angiographic studies were repeated in six patients after 6 months of follow-up and showed patent vessels in five and reoccurrence of a slight renal-artery stenosis in one. In one patient angiographic control studies done after 3 months showed an occluded renal artery. In five patients mean pressure gradient across the renal-artery stenoses was 89 +/- 22.8 mm Hg before percutaneous transluminal dilatation and 16.4 +/- 18.5 mm Hg after being controlled for 6 months. Our results indicate that percutaneous transluminal dilatation may be valuable in the treatment of renovascular hypertension.

• Authors: U Kuhlmann, W Vetter, J Furrer, U Lütolf, W Siegenthaler, A Grüntzig
• Journal: Annals of internal medicine (Ann Intern Med) Vol. 92 Issue 1 Pg. 1-6 (Jan 1980) ISSN: 0003-4819 [Print] United States
• PMID: 7350853 (Publication Type: Journal Article)

Chemical References

• Antihypertensive Agents
• Creatinine
• Renin

Topics

• Aged
• Angiography
• Antihypertensive Agents (therapeutic use)
• Blood Pressure
• Catheterization (methods)
• Creatinine (blood)
• Dilatation
• Follow-Up Studies
• Humans
• Hypertension, Renal (therapy)
• Hypertension, Renovascular (diagnostic imaging, etiology, therapy)
• Male
• Middle Aged
• Renal Artery Obstruction (complications, diagnostic imaging, therapy)
• Renin (blood)