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Single oral-dose metronidazole therapy for trichomonas vaginitis in adolescents.

Abstract
A group of 218 adolescent girls in a detention setting was treated for vaginal trichomoniasis with a single 2-g oral dose of metronidazole, a successful therapeutic approach in infected adults. This method of treatment has not been reported in teenagers. The initial diagnosis and posttreatment test for cure were based on a Gram stain of vaginal secretions. Administration of the medication and avoidance of reinfection were controlled. The test for cure was done 5 days after treatment. The cure rate under these conditions was 98%. Side effects were infrequent and minor. Our results suggest that single-dose therapy not only avoids the problem of patient compliance but is effective, safe, and less costly than a standard 7- or 10- day regimen.
AuthorsW L Minkowski, C J Baker, L Friedlander
JournalJournal of adolescent health care : official publication of the Society for Adolescent Medicine (J Adolesc Health Care) Vol. 2 Issue 1 Pg. 41-4 (Sep 1981) ISSN: 0197-0070 [Print] United States
PMID7333943 (Publication Type: Journal Article)
Chemical References
  • Metronidazole
Topics
  • Administration, Oral
  • Adolescent
  • Child
  • Female
  • Humans
  • Metronidazole (administration & dosage)
  • Trichomonas Vaginitis (drug therapy)

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