[Search for the heterogenetic Forssman antigen in human breast tumor tissue].

Abstract

The complement fixation test was used to examine 80 human mammary tumors for the presence of heterogeneous Forssman antigen: 62 cases of cancers of different malignancy (adenocarcinoma, solid tumors), 13 cases of fibroadenomas and 5 cases of fibrocystic mastopathies. Subject to study was also normal tissue of the mammary gland. Forssman antigen was not found in all the tumors tested, as it was not detected in tissues of the normal mammary gland. Therefore the process of transformation of normal cells to tumor ones is not accompanied by the occurrence in them of heterogenous Forssman antigen.

• Authors: M S Berdinskikh, R P Pavliuchenkova, A S Kiseleva, A M Kulakova, P N Kosiakov
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 92 Issue 12 Pg. 710-1 (Dec 1981) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Poiski geterogennogo antigena Forssmana v tkaniakh opukholeĭ molochnoĭ zhelezy cheloveka.
• PMID: 7326421 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antigens, Neoplasm
• Forssman Antigen

Topics

• Adenocarcinoma (immunology)
• Adenofibroma (immunology)
• Antigens, Neoplasm (analysis)
• Breast (immunology)
• Breast Neoplasms (immunology)
• Complement Fixation Tests
• Female
• Fibrocystic Breast Disease (immunology)
• Forssman Antigen (analysis)
• Humans