Changes in conglutinin, immunoconglutinin, complement C3 and fibronectin concentrations in cattle acutely infected with Babesia bovis.

Abstract

Further pathophysiological studies of the hypotensive shock syndrome associated with acute Babesia bovis infection in cattle have demonstrated changes in the plasma concentrations of conglutinin, complement C3, fibronectin and immunoconglutinin. Decreases in the first three components are presumably due to their contribution towards intravascular sludging of infected erythrocytes within the microvascular system during the acute phase of infection. In contrast, the increase in fibronectin and immunoconglutinin in the recovery phase suggests the involvement of these proteins in the reticulo-endothelial clearance of infected or damaged erythrocytes, immune complexes and cryofibrinogen.

• Authors: B V Goodger, I G Wright, D F Mahoney
• Journal: The Australian journal of experimental biology and medical science (Aust J Exp Biol Med Sci) Vol. 59 Issue Pt 5 Pg. 531-8 (Oct 1981) ISSN: 0004-945X [Print] Australia
• PMID: 7325886 (Publication Type: Journal Article)

Chemical References

• Collectins
• Complement C3
• Fibronectins
• Serum Globulins
• conglutinin

Topics

• Acute Disease
• Animals
• Babesiosis (blood, immunology)
• Cattle
• Cattle Diseases (blood, immunology)
• Collectins
• Complement C3 (analysis)
• Complement Fixation Tests
• Fibronectins (blood)
• Serum Globulins (analysis)