[Sweet's syndrome: report of two cases (author's transl)].

Abstract

In 1964 Sweet described a new syndrome, characterized by the association of fever, neutrophilic leukocytosis, erythematous plaque affecting the extremities, neck and face, with histologically verified polymorphonuclear perivascular dermal infiltrates and a rapid response to corticosteroids. Although some 100 cases have since then been described the pathogenesis remains obscure. We present two cases which showed all criteria for Sweet's syndrome, in which the initial presentation of acute onset with fever, multiple skin lesions and especially the poor general state on one, made use at first think of an infectious process such as staphylococcal or gonococcal sepsis, in which case diagnosis must be differential. Only when the causal agent is known and an early skin biopsy is done can correct diagnosis and treatment be established.

• Authors: J M Miró Meda, J Mensa Pueyo, M Alsina Gibert, M A Moreno Camacho, F Segura Porta, J García San Miguel
• Journal: Medicina clinica (Med Clin (Barc)) Vol. 77 Issue 2 Pg. 77-80 (Jun 25 1981) ISSN: 0025-7753 [Print] Spain
• Vernacular Title: Síndrome de Sweet. Presentación de dos casos.
• PMID: 7321631 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Adrenal Cortex Hormones

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Diagnosis, Differential
• Erythema (complications)
• Female
• Fever (complications)
• Humans
• Leukocytosis (complications)
• Middle Aged
• Neutrophils
• Skin (pathology)
• Skin Diseases, Infectious (diagnosis)
• Syndrome