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Response of metastatic cloacogenic carcinoma to treatment with semustine.

Abstract
A case of cloacogenic carcinoma of the anorectal junction with pulmonary metastases is presented. Treatment with Semustine (Methyl-CCNU) resulted in a partial response lasting 15 months. Cloacogenic carcinoma is an uncommon neoplasm against which only a few chemotherapeutic agents have been tried. Semustine should be considered in the treatment of metastatic cloacogenic carcinoma.
AuthorsS Zimm, G L Wampler
JournalCancer (Cancer) Vol. 48 Issue 12 Pg. 2575-6 (Dec 15 1981) ISSN: 0008-543X [Print] United States
PMID7306917 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Nitrosourea Compounds
  • Semustine
  • Fluorouracil
Topics
  • Anus Neoplasms (pathology)
  • Carcinoma, Transitional Cell (drug therapy, mortality, secondary)
  • Drug Administration Schedule
  • Female
  • Fluorouracil (therapeutic use)
  • Humans
  • Lung Neoplasms (drug therapy, mortality, secondary)
  • Middle Aged
  • Nitrosourea Compounds (therapeutic use)
  • Rectal Neoplasms (pathology)
  • Semustine (therapeutic use)
  • Time Factors

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