Undiagnosed bleeding states and medical treatment.

Abstract

Relatively little attention has been placed in mild hemophilia in the orthopedic literature even though there are probably an equal number of patients with mild as compared to classic manifestations. Mild hemophilia and similar related conditions frequently are undiagnosed and may represent major problems and if associated with surgery, catastrophic results. Patients with milder bleeding diatheses may not have a diagnosis made until late in life. Mild hemophilia and hemophiloid conditions are defined and typical findings are given. Other causes of intra or postoperative hemorrhagic states are mentioned. Three case reports of mild Factor VIII and Factor XI deficiency, undiagnosed prior to the author's medical treatment, are presented. Knowledge of the typical historical findings, diagnostic methods, and proper treatment of patients seeking medical treatment with mild hemophilia, hemophiloid and similar conditions explaining hemorrhage following trauma and intra and postoperatively will help to prevent undesirable results as well as severe complications.

• Authors: C V Spear, J A Mason, S R Williamson, R S Neff, L J Comeaux Jr, F W Gwathmey
• Journal: Clinical orthopaedics and related research (Clin Orthop Relat Res) 1978 Jul-Aug Issue 134 Pg. 249-60 ISSN: 0009-921X [Print] United States
• PMID: 729252 (Publication Type: Journal Article)

Chemical References

• Prothrombin
• Thromboplastin

Topics

• Adult
• Blood Coagulation Tests
• Child
• Female
• Hemophilia A (complications, diagnosis, genetics)
• Hemorrhage (etiology, therapy)
• Humans
• Male
• Middle Aged
• Postoperative Complications (etiology)
• Prothrombin (analysis)
• Surgical Procedures, Operative
• Thromboplastin (analysis)