[Recurrent meningococcal meningitis associated with complement C6 deficiency (author's transl)].

Abstract

In a young West-Indian woman recurrent meningococcal meningitis was found to be associated with hereditary deficiency of the C6 component of complement. Such an association has already been reported in 8 patients, all black. Measuring the total haemolytic complement would provide an easy way of detecting high risk subjects, who would benefit from immunization.

• Authors: M F Avril, J Lebas, B Autran, J Modai
• Journal: La Nouvelle presse medicale (Nouv Presse Med) Vol. 10 Issue 37 Pg. 3057-9 (Oct 17 1981) ISSN: 0301-1518 [Print] France
• Vernacular Title: Méningite à méningocoques récidivante associée à un déficit en 6e composant du complément.
• PMID: 7290963 (Publication Type: Case Reports, Journal Article)

Chemical References

• Complement C6
• Complement System Proteins

Topics

• Adult
• Black People
• Blood Bactericidal Activity
• Complement C6 (deficiency, genetics)
• Complement System Proteins (analysis)
• Female
• Humans
• Meningitis, Meningococcal (genetics, immunology, prevention & control)
• Middle Aged
• Recurrence