Abstract |
The results of treatment of 29 patients with Darier's disease with the aromatic retinoid Ro 10-9359 are reported. Therapeutic tests for a period of more than 18 months seem to justify its use in Darier's disease. With a modest dose it is possible to keep the symptoms at an acceptable level, i. e., 50% clearing or more without too troublesome side effects. Because of the side effects the dosage must be fixed individually. It is pointed out that with the development of Ro 10-9359, an efficient remedy for Darier's disease has become available for the first time.
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Authors | J V Christiansen, P Holm, R Møller, F Reymann, H Schmidt |
Journal | Dermatologica
(Dermatologica)
Vol. 163
Issue 2
Pg. 164-8
( 1981)
ISSN: 0011-9075 [Print] Switzerland |
PMID | 7286356
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Darier Disease
(drug therapy)
- Dose-Response Relationship, Drug
- Etretinate
(adverse effects, therapeutic use)
- Female
- Humans
- Male
- Middle Aged
- Tretinoin
(analogs & derivatives)
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