[Effects of tilidin and naloxone on pulmonary function (author's transl)].

Abstract

The respiratory depressant effect of tilidine (valoron) was investigated in anaesthetized patients. One hundred mg of tilidine had a slight respiratory depressant effect which was without importance in awake subjects. The respiratory depression caused by tilidine could be antagonized by naloxone while the analgesic effect was maintained. This suggests a dissociation of the mechanisms responsible for the respiratory and the analgesic actions.

• Authors: H Schaer, K Baasch
• Journal: Der Anaesthesist (Anaesthesist) Vol. 27 Issue 11 Pg. 538-9 (Nov 1978) ISSN: 0003-2417 [Print] Germany
• Vernacular Title: Wirkungen von Tilidin und Naloxone auf die Atemfunktion.
• PMID: 727427 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cyclohexanecarboxylic Acids
• Naloxone
• Tilidine

Topics

• Adolescent
• Adult
• Analgesia
• Anesthesia, General
• Cyclohexanecarboxylic Acids (pharmacology)
• Depression, Chemical
• Drug Antagonism
• Humans
• Middle Aged
• Naloxone (pharmacology)
• Respiration (drug effects)
• Tilidine (pharmacology)