Pneumatosis cystoides intestinalis: a complication of systemic chemotherapy.

Abstract

A case of pneumatosis cystoides intestinalis following administration of chemotherapy for Hodgkin's disease is presented. Because of a poor response to nonoperative management, a subtotal colectomy was performed. Although the pathogenesis of pneumatosis cystoides intestinalis is not entirely clear, it seems likely that, in this case, mucosal ulceration secondary to methyl-gag allowed intraluminal air to dissect into the intestinal wall and surrounding retroperitoneal tissues. Because pneumatosis cystoides intestinalis is often reversible and self-limited, fecal diversion in lieu of bowel resection is entertained as a possible alternative in the operative management of selected cases. In the case presented resection was performed because of extent of the pathologic process.

• Authors: L E Shindelman, S A Geller, N Wisch, J J Bauer
• Journal: The American journal of gastroenterology (Am J Gastroenterol) Vol. 75 Issue 4 Pg. 270-4 (Apr 1981) ISSN: 0002-9270 [Print] United States
• PMID: 7258172 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Antineoplastic Agents (adverse effects, therapeutic use)
• Hodgkin Disease (drug therapy)
• Humans
• Ileum (pathology)
• Male
• Mucous Membrane (pathology)
• Pneumatosis Cystoides Intestinalis (chemically induced, pathology)