HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Cytogenetic effect of a number of pesticides in a human peripheral blood lymphocyte culture with a varying initial level of chromosome aberrations].

Abstract
The paper deals with results of studies in the mutagenic activity of pesticides (polymarzin, cuprozin and pyrimor) in the human peripheral lymphocyte culture at various frequency of "spontaneous" chromosome aberrations. Only pyrimor is determined to possess the cytogenetic action in the used test-system. It is shown that the intensity of the pyrimor-induced cytogenetic effect depends on the initial level of aberrant metaphases in the control cultures obtained from two different persons. The previously made conclusion on the potential mutagenic danger of pyrimor is confirmed on the basis of studies of its cytogenetic activity in mice bone marrow cells.
AuthorsM A Pilinskaia
JournalTSitologiia i genetika (Tsitol Genet) 1981 Mar-Apr Vol. 15 Issue 2 Pg. 82-4 ISSN: 0564-3783 [Print] Ukraine
Vernacular TitleIzuchenie tsitogeneticheskogo éffekta riada pestitsidov v kul'ture limfotsitov perifericheskoĭ krovi cheloveka pri razlichnom iskhodnom urovne aberratsiĭ khromosom.
PMID7233556 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Pesticides
Topics
  • Cells, Cultured
  • Chromosome Aberrations
  • Humans
  • Lymphocytes (drug effects)
  • Metaphase (drug effects)
  • Pesticides (pharmacology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: