Oral butorphanol tartrate for the long-term treatment of out-patients with moderate to severe cancer pain.

The safety, tolerance and analgesic efficacy of multiple oral doses of butorphanol tartrate for the long-term treatment of cancer pain were evaluated in this open study. Thirty-five patients were treated with various doses (1 to 12 tablets per day) for 4 to 147 days. The median pain relief was fair, good, very good or excellent in 51% of the patients and poor in 49% of the patients. Global assessments were very similar. No clinically significant changes in blood pressure, weight, blood and urine chemistries were observed. Seventeen patients reported side-effects (only sedation and dry mouth) ranging from mild to severe.
AuthorsJ De la Garza
JournalThe Journal of international medical research (J Int Med Res) Vol. 9 Issue 2 Pg. 124-7 ( 1981) ISSN: 0300-0605 [Print] ENGLAND
PMID7227623 (Publication Type: Journal Article)
Chemical References
  • Butorphanol
  • Adult
  • Aged
  • Butorphanol
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms (complications)
  • Outpatients
  • Pain (drug therapy)
  • Time Factors

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