[The effect of tiofedrine on brain perfusion in patients with cerebrovascular insufficiency].

Abstract

The influence of intravenous tinofedrine (0.12 to 0.17 mg/kg body-weight) on cerebral blood flow has been investigated in 23 patients (mean age 65 years) with subacute cerebral infarction. The mean cerebral blood flow increased significantly by 20% in the infarcted hemisphere during a treatment period of 12 days. Clinically an improvement of an initially depressed vigilance level was established which was quantified psychopathometrically in 4 patients.

• Authors: E Ott, H Lechner
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 36 Issue 4 Pg. 124-6 (Feb 15 1981) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Die Wirkung von Tinofedrin auf die Hirndurchblutung bei Patienten mit zerebrovaskulärer Insufffizienz.
• PMID: 7222859 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Thiophenes
• tinofedrine

Topics

• Aged
• Cerebral Infarction (drug therapy)
• Cerebrovascular Circulation (drug effects)
• Female
• Humans
• Infusions, Parenteral
• Male
• Middle Aged
• Thiophenes (administration & dosage, therapeutic use)