[Combination chemotherapy in the adjuvant treatment of disseminated breast cancer].

Abstract

The results of clinical studies are presented on the combined chemotherapy in spread breast cancer, conducted according to the following three schedules: 1. thiophosphamide, carminomycin, vincristine, ftorafur, prednisolone, 2. diiodobenzoTEPA, carminomycin, vincristine, ftorafur, prednisolone, 3. methotrexate, cyclophosphane, vincristine, ftorafur, prednisolone. The combined chemotherapy in the complex treatment of 91 patients with spread breast cancer was found to be effective in 33-40% of cases. Primary tumors of the mammary gland and metastases in soft tissues, lymph nodes were mostly sensitive to the combined chemotherapy, metastases in bones and visceral organs--less sensitive. Schedules 2 and 3 proved to be the least toxic ones.

• Authors: O V Sviatukhina, G E Izmaĭlova
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 27 Issue 3 Pg. 43-8 ( 1981) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Kombinirovannaia khimioterapiia v kompleksnom lechenii rasprostranennogo raka molochnoĭ zhelezy.
• PMID: 7222522 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Aged
• Antineoplastic Agents (administration & dosage, adverse effects)
• Breast Neoplasms (drug therapy)
• Castration
• Drug Therapy, Combination
• Female
• Humans
• Lymphatic Metastasis
• Mastectomy
• Middle Aged
• Time Factors