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Allergenic potential of abietic acid, colophony and pine resin-HA. Clinical and experimental studies.

Abstract
Resin acids are considered to be the main allergens in colophony (rosin). Tall oils also contain resin acids and may then be potential sensitizers. A resin acid concentrate (pine resin-HA) together with Chinese colophony were included in our standard series and applied on 563 patients with contact dermatitis. Fourteen showed an isolated sensitivity to colophony and two to pine resin-HA. Six patients reacted to both test compounds. Guinea pig maximization tests (Magnusson & Kligman 1969) showed that pine resin-HA (2 series) was a grade I allergen, abietic acid a grade III allergen and colophony a grade IV allergen. The risk that the resin acids in tall oils would induce contact sensitivity to workers exposed to tall oil-containing products like cutting fluids and cleansing agents is considered to be minimal.
AuthorsA T Karlberg, A Boman, J E Wahlberg
JournalContact dermatitis (Contact Dermatitis) Vol. 6 Issue 7 Pg. 481-7 (Dec 1980) ISSN: 0105-1873 [Print] England
PMID7214893 (Publication Type: Journal Article)
Chemical References
  • Allergens
  • Plant Oils
  • Resins, Plant
  • tall oil
Topics
  • Allergens
  • Animals
  • Dermatitis, Atopic (chemically induced)
  • Guinea Pigs
  • Humans
  • Patch Tests
  • Plant Oils
  • Resins, Plant (adverse effects, immunology)
  • Trees

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