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Wegener's granulomatosis and relapsing polychondritis: a case report.

AbstractRelapsing polychondritis, a rare disorder characterized by inflammation of cartilaginous tissue, is often associated with vasculitic features. Wegener's granulomatosis is an uncommon form of vasculitis, usually responsive to treatment with cyclophosphamide. A 59-yr-old man with relapsing polychondritis, initially well controlled by corticosteroid therapy, developed pulmonary infiltrates and glomerulonephritis. After pathological confirmation of Wegener's granulomatosis, cyclophosphamide therapy was instituted and remission achieved.
AuthorsP Small, M Black, M Davidman, M L de Champlain, M A Kapusta, H Kreisman
JournalThe Journal of rheumatology (J Rheumatol) 1980 Nov-Dec Vol. 7 Issue 6 Pg. 915-8 ISSN: 0315-162X CANADA
PMID7205833 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cyclophosphamide
Topics
  • Cyclophosphamide (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Polychondritis, Relapsing (complications, drug therapy)
  • Wegener Granulomatosis (complications, drug therapy)