[Prevention of aspiration pneumonia with cimetidine].

Abstract

Aspiration of gastric acid is one of the most feared narcosis complications. The currently practiced methods of prophylaxis did not reduce the frequency of aspiration pneumonitis. In a prospective randomised study orally and intramuscularly given Cimetidine significantly reduced the toxicity of stomach contents. The intramuscular route proved to be superior. Preoperative prophylactic use of Cimetidine can be a useful method to reduce the frequency of Mendelson's syndrome without disadvantages.

• Authors: M Tryba, F Yildiz, M Zenz, M Schwerdt
• Journal: Der Anaesthesist (Anaesthesist) Vol. 31 Issue 10 Pg. 584-7 (Oct 1982) ISSN: 0003-2417 [Print] Germany
• Vernacular Title: Prophylaxe der Aspirationspneumonie mit Cimetidin.
• PMID: 7181084 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Guanidines
• Cimetidine

Topics

• Administration, Oral
• Adult
• Cimetidine (administration & dosage, therapeutic use)
• Female
• Guanidines (therapeutic use)
• Humans
• Injections, Intramuscular
• Male
• Middle Aged
• Pneumonia, Aspiration (prevention & control)
• Postoperative Complications (prevention & control)