[Protective action of a combined preparation and staphylococcal anatoxin in reproducing a local staphylococcal infection in white mice].

Abstract

In experimental local staphylococcal infection in white mice, previously immunized with staphylococcal toxoid and the combined preparation (staphylococcal toxoid + protective somatic staphylococcal antigen), the advantage of the latter in protecting the animals against infection with Staphylococcus aureus belonging to different phage groups has been revealed. Immunization with the combined preparation, carried out in 2 injections, has been found to stimulate antimicrobial immunity, simultaneously with antitoxic one, which indicates the expediency of the further study of the combined preparation.

• Authors: T I Berlovskaia, N V Karnitskaia, A K Akatov, V I Ermolov
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 10 Pg. 53-6 (Oct 1982) ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Zashchitnoe deĭstvie assotsiirovannogo preparata i stafilokokkovogo anatoksina pri vosproizvedenii mestnoĭ stafilokokkovoĭ infektsii na belykh myshakh.
• PMID: 7180254 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antigens, Bacterial
• Staphylococcal Toxoid

Topics

• Animals
• Antigens, Bacterial (immunology)
• Bacteriophage Typing
• Immunization
• Immunization Schedule
• Mice
• Staphylococcal Infections (immunology, prevention & control)
• Staphylococcal Toxoid (immunology)
• Staphylococcus aureus (classification)
• Time Factors