Effects of lysine-vasopressin and 1-deamino-8-D-arginine-vasopressin on memory in healthy individuals and diabetes insipidus patients.

Abstract

Central diabetes insipidus (DI) patients showed impairments in short- and long-term memory functions, but not in attention and concentration, as compared to healthy individuals. A single i.m. injection or sub-chronic intranasal administration of either lysine-vasopressin (LVP) or 1-deamino-8-D-arginine-vasopressin (DDAVP) normalized the disturbed memory functions in DI patients. These peptides also improved memory functions in healthy individuals.

• Authors: F Laczi, Z Valkusz, F A Lászlo, A Wagner, T Járdánházy, A Szász, J Szilárd, G Telegdy
• Journal: Psychoneuroendocrinology (Psychoneuroendocrinology) Vol. 7 Issue 2-3 Pg. 185-93 ( 1982) ISSN: 0306-4530 [Print] England
• PMID: 7178372 (Publication Type: Journal Article)

Chemical References

• Arginine Vasopressin
• Lypressin
• Deamino Arginine Vasopressin

Topics

• Administration, Intranasal
• Adult
• Arginine Vasopressin (pharmacology)
• Deamino Arginine Vasopressin (administration & dosage, pharmacology)
• Diabetes Insipidus (physiopathology)
• Female
• Humans
• Injections, Intramuscular
• Lypressin (administration & dosage, pharmacology)
• Male
• Memory (drug effects)
• Middle Aged