Topical retinoic acid in the treatment of corneal xerophthalmia.

Abstract

Eight children with corneal xerophthalmia (x2 or x3A) received standard high-protein diets and massive systemic vitamin A therapy. Retinoic acid, 0.1% in oil, was applied daily to one eye, and oil alone to the other. Topical retinoic acid proved safe and effective in speeding corneal healing, especially during the first critical days.

• Authors: A Sommer, N Emran
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 86 Issue 5 Pg. 615-7 (Nov 1978) ISSN: 0002-9394 [Print] United States
• PMID: 717517 (Publication Type: Journal Article)

Chemical References

• Dietary Proteins
• Vitamin A
• Tretinoin

Topics

• Administration, Topical
• Animals
• Child
• Child, Preschool
• Dietary Proteins (therapeutic use)
• Female
• Humans
• Male
• Rats
• Tretinoin (therapeutic use)
• Vitamin A (analogs & derivatives, therapeutic use)
• Vitamin A Deficiency (diet therapy, drug therapy)
• Xerophthalmia (diet therapy, drug therapy)