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Problems in the management of patients with artificial valves during pregnancy.

Abstract
During the past 15 years, 12 patients with prosthetic valves were treated during 18 pregnancies in the four Dublin maternity hospitals. These patients were on long-term anticoagulants and their pregnancies were reviewed to assess the problems associated with anticoagulation. One baby had warfarin embryopathy, six pregnancies ended in spontaneous abortions and there were two intrauterine deaths. On the basis of the findings a policy on the most appropriate anticoagulant regimen in such cases was formulated.
AuthorsH O'Neill, S Blake, D Sugrue, D Macdonald
JournalBritish journal of obstetrics and gynaecology (Br J Obstet Gynaecol) Vol. 89 Issue 11 Pg. 940-3 (Nov 1982) ISSN: 0306-5456 [Print] England
PMID7171503 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Warfarin
  • Heparin
Topics
  • Abortion, Spontaneous (chemically induced)
  • Adult
  • Female
  • Fetal Death (chemically induced)
  • Heart Valve Prosthesis
  • Heparin (adverse effects)
  • Humans
  • Maternal-Fetal Exchange
  • Pregnancy
  • Pregnancy Complications, Cardiovascular (drug therapy)
  • Warfarin (adverse effects)

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