The effect of beclomethasone diproprionate on bronchial hyperreactivity.

Abstract

BDP is a useful treatment for asthma, but the mechanism of its action is unknown. Routine estimations of bronchial sensitivity to histamine aerosols showed that there was a decrease in bronchial hyperreactivity in 11 out of 14 cases given BDP as a routine treatment. The results are significant by Student's t-test (P less than .001) and reveal one mechanism by which BDP can act in the lungs.

• Authors: P S Clarke
• Journal: The Journal of asthma : official journal of the Association for the Care of Asthma (J Asthma) Vol. 19 Issue 2 Pg. 91-3 ( 1982) ISSN: 0277-0903 [Print] England
• PMID: 7118817 (Publication Type: Journal Article)

Chemical References

• Aerosols
• Histamine
• Beclomethasone

Topics

• Adolescent
• Adult
• Aerosols
• Aged
• Asthma (chemically induced, drug therapy)
• Beclomethasone (administration & dosage, therapeutic use)
• Female
• Forced Expiratory Volume
• Histamine
• Humans
• Male
• Middle Aged
• Respiratory Hypersensitivity (drug therapy)