Abstract |
Sixty-three outpatients shedding eggs of S. haematobium were treated with 35 mg/kg oltipraz given in two divided doses on a single day (Niamey). 75% of the patients were egg-negative at one month and 88.9% at three months. Urinary egg excretion was markedly reduced (98%) and the mean egg count per 10 ml urine decreased from 33 before dosing to 0.6 at two months. Oltipraz thus appears to be a most interesting drug for urinary schistosomiasis
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Authors | J L Rey, B Sellin, E Simonkovich, G Charmot |
Journal | Bulletin de la Societe de pathologie exotique et de ses filiales
(Bull Soc Pathol Exot Filiales)
1982 Mar-Apr
Vol. 75
Issue 2
Pg. 179-82 France |
Vernacular Title | Résultats obtenus sur S. haematobium par l'Oltipraz au Niger. |
PMID | 7105290
(Publication Type: Journal Article)
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Chemical References |
- Pyrazines
- Schistosomicides
- Thiones
- Thiophenes
- oltipraz
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Topics |
- Adolescent
- Adult
- Child
- Female
- Humans
- Male
- Niger
- Pyrazines
(therapeutic use)
- Schistosoma haematobium
- Schistosomiasis
(drug therapy)
- Schistosomicides
(therapeutic use)
- Thiones
- Thiophenes
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