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[Results obtained on S. haematobium by Oltipraz in Niger (author's transl)].

Abstract
Sixty-three outpatients shedding eggs of S. haematobium were treated with 35 mg/kg oltipraz given in two divided doses on a single day (Niamey). 75% of the patients were egg-negative at one month and 88.9% at three months. Urinary egg excretion was markedly reduced (98%) and the mean egg count per 10 ml urine decreased from 33 before dosing to 0.6 at two months. Oltipraz thus appears to be a most interesting drug for urinary schistosomiasis
AuthorsJ L Rey, B Sellin, E Simonkovich, G Charmot
JournalBulletin de la Societe de pathologie exotique et de ses filiales (Bull Soc Pathol Exot Filiales) 1982 Mar-Apr Vol. 75 Issue 2 Pg. 179-82 France
Vernacular TitleRésultats obtenus sur S. haematobium par l'Oltipraz au Niger.
PMID7105290 (Publication Type: Journal Article)
Chemical References
  • Pyrazines
  • Schistosomicides
  • Thiones
  • Thiophenes
  • oltipraz
Topics
  • Adolescent
  • Adult
  • Child
  • Female
  • Humans
  • Male
  • Niger
  • Pyrazines (therapeutic use)
  • Schistosoma haematobium
  • Schistosomiasis (drug therapy)
  • Schistosomicides (therapeutic use)
  • Thiones
  • Thiophenes

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