[Clinical evaluation of cefoxitin in treatment of infections in obstetric and gynecologic field (author's transl)].

Abstract

Ten patients (8 with moderate or severe infections, 2 for prevention of postoperative infections) were treated with cefoxitin. The patients were given cefoxitin of 2 approximately 9 g, given once, or in 2 approximately 3 divided doses. Clinical efficacy was good in 7 cases, fair in 2 and poor in 1. Transient nausea and vomiting occurred in 1 patient when a direct intrauterine injection (1 g of cefoxitin) was given, however, no side effects were observed in the other patients. The result of this study demonstrates that cefoxitin when given massively is effective in achieving bacteriologic and clinical cure in treatment of infections and for prevention of postoperative infections in the field of obstetrics and gynecology.

• Authors: N Cho, H Araki, H Saito, Y Sanai, S Oishi, K Komatsuzaki, K Takasaki, I Matsumura
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 35 Issue 4 Pg. 884-91 (Apr 1982) ISSN: 0368-2781 [Print] Japan
• PMID: 7097986 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cefoxitin

Topics

• Adult
• Bacterial Infections (drug therapy, prevention & control)
• Cefoxitin (administration & dosage, therapeutic use)
• Cesarean Section
• Female
• Genital Diseases, Female (drug therapy)
• Humans
• Infusions, Parenteral
• Middle Aged
• Postoperative Complications (prevention & control)
• Pregnancy
• Premedication
• Puerperal Infection (drug therapy)