Mechanism of hemolysis by Renalin, a CAMP-like protein from Corynebacterium renale.

Abstract	Synergistic hemolysis of sheep erythrocytes caused by Staphylococcus aureus and Corynebacterium renale resulted from the combined action of extracellular staphylococcal sphingomyelinase C and a newly described extracellular agent of C. renale (renalin). The affinity of renalin for ceramide was considered to play a key role in causing hemolysis in erythrocytes in which ceramide had been generated through the action of sphingomyelinase C.
Authors	A W Bernheimer, L S Avigad
Journal	Infection and immunity (Infect Immun) Vol. 36 Issue 3 Pg. 1253-6 (Jun 1982) ISSN: 0019-9567 [Print] United States
PMID	7095849 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References	Bacterial Proteins Ceramides Drug Combinations Hemolysin Proteins Renalin Hydrogen Peroxide Sphingomyelin Phosphodiesterase Peracetic Acid Acetic Acid
Topics	Acetic Acid Bacterial Proteins (pharmacology) Ceramides (metabolism) Corynebacterium Drug Combinations Erythrocyte Membrane (drug effects) Erythrocytes (drug effects) Hemolysin Proteins Hydrogen Peroxide Molecular Weight Peracetic Acid Sphingomyelin Phosphodiesterase (metabolism) Staphylococcus aureus (enzymology)

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