Metastatic thymoma with myasthenia gravis: complete remission with combination chemotherapy.

Abstract

A 29-year-old male developed myasthenia gravis 29 months after resection of a "benign" mediastinal thymoma. Metastatic thymoma was found in the pleura 45 months after the initial surgical resection. Combination chemotherapy with cyclophosphamide and doxorubicin produced a complete remission of the metastatic thymoma which has continued for 13 months. Concurrently, there has been a marked increase in neuromuscular function.

• Authors: W M Butler, L F Diehl, H G Taylor, M D Weltz
• Journal: Cancer (Cancer) Vol. 50 Issue 3 Pg. 419-22 (Aug 01 1982) ISSN: 0008-543X [Print] United States
• PMID: 7093885 (Publication Type: Case Reports, Journal Article)

Chemical References

• Doxorubicin
• Cyclophosphamide

Topics

• Adult
• Cyclophosphamide (therapeutic use)
• Doxorubicin (therapeutic use)
• Drug Administration Schedule
• Drug Therapy, Combination
• Follow-Up Studies
• Humans
• Male
• Myasthenia Gravis (complications)
• Thymoma (complications, drug therapy, pathology)
• Thymus Neoplasms (complications, drug therapy, pathology)