HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Vitamin B6 deficiency as related to oxalate-synthesizing enzymes in growing rats.

Abstract
Chronic vitamin B6 deficiency in male rats, 1, 2 and 3 months of age, led to increases in the activities of liver glycolate oxidase and kidney glycolate dehydrogenase as compared to pair-fed controls. Lactate dehydrogenase activity either decreased or showed no change in all three age groups. It is postulated that hyperoxaluria observed in vitamin B6 deficiency is due to two different pathways operative in the liver and kidney separately. A general increase seen in the enzyme activities of livers and kidneys of B6-deficient and pair-fed rats was age related.
AuthorsM S Murthy, H S Talwar, S K Thind, R Nath
JournalAnnals of nutrition & metabolism (Ann Nutr Metab) Vol. 26 Issue 3 Pg. 201-8 ( 1982) ISSN: 0250-6807 [Print] Switzerland
PMID7051948 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Oxalates
  • Oxalic Acid
  • Alcohol Oxidoreductases
  • glycolic acid dehydrogenase
  • L-Lactate Dehydrogenase
  • glycollate oxidase
Topics
  • Alcohol Oxidoreductases (metabolism)
  • Animals
  • Kidney (enzymology)
  • L-Lactate Dehydrogenase (metabolism)
  • Liver (enzymology)
  • Male
  • Oxalates (biosynthesis)
  • Oxalic Acid
  • Rats
  • Rats, Inbred Strains (growth & development)
  • Vitamin B 6 Deficiency (enzymology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: