[Trails with levamisole to stimulate immunity against Newcastle disease in poultry].

Abstract

Attempts to stimulate the immunity against Newcastle disease in birds aged 2 months, of the Leghorn breed, were carried out. It was found that levamisol at the rate of 3 mg/kg body weight given once, parenterally, 24 hours prior to or after the immunization of the birds with a live La Sota vaccine or given three times, parenterally or orally, did not stimulate the humoral immune response. No differences were found in the level of the total protein, protein fractions, and the titer of the hemagglutinating antibodies between the test and the control birds. There was, however, prolongation of the time of effective immunity in the levamisol-treated and vaccinated birds as against the birds that were vaccinated against Newcastle disease only. Discussed in the possible mechanism of stimulating the immunity with levamisol.

• Authors: I Chenchev, G Kostov, R Cholakova, M Bonovska
• Journal: Veterinarno-meditsinski nauki (Vet Med Nauki) Vol. 18 Issue 10 Pg. 104-8 ( 1981) ISSN: 0324-1068 [Print] Bulgaria
• Vernacular Title: Opiti za stimulirane na imuniteta sreshtu psevdochuma po ptitsite s levamizol.
• PMID: 7048726 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Viral Vaccines
• Levamisole

Topics

• Animals
• Clinical Trials as Topic (veterinary)
• Immunity (drug effects)
• Immunization (veterinary)
• Levamisole (administration & dosage, immunology)
• Newcastle Disease (prevention & control)
• Newcastle disease virus (immunology)
• Time Factors
• Viral Vaccines (administration & dosage)