Preoperative and postoperative renin levels in coarctation of the aorta.

Abstract

We studied plasma renin activity (PRA) in eight children before and after surgical correction of aortic coarctation. These eight children underwent a combination of low-sodium diet and diuresis before surgery, and PRA was measured shortly thereafter. Thirty-two to 51 months after successful surgical correction, PRA was measured again. The mean PRA was 21.4 +/- 1.3 ng/ml/hour (+/- SD) preoperatively and 5.5 +/- 1.5 ng/ml/hour postoperatively. These findings provide further evidence of the significance of increased renin-angiotensin activity in patients with aortic coarctation.

• Authors: F B Parker Jr, D H Streeten, B Farrell, M S Blackman, H M Sondheimer, G H Anderson Jr
• Journal: Circulation (Circulation) Vol. 66 Issue 3 Pg. 513-4 (Sep 1982) ISSN: 0009-7322 [Print] United States
• PMID: 7046989 (Publication Type: Journal Article)

Chemical References

• Diuretics
• Angiotensin II
• Renin

Topics

• Adolescent
• Angiotensin II (blood)
• Aortic Coarctation (blood, complications, surgery)
• Child
• Child, Preschool
• Diet, Sodium-Restricted
• Diuretics (therapeutic use)
• Humans
• Hypertension (complications)
• Renin (blood)