Xerostomia in Sjögren's syndrome treated with Sali-Synt. A double-blind cross-over trial.

Abstract

In a double-blind cross-over trial, a new synthetic saliva Sali-Synt was compared with placebo for the treatment of xerostomia in Sjögren's syndrome. Sali-Synt may soothe the pain in the mouth and reduces sleep disturbances better than placebo, but no statistically significant differences were found. Seven patients of 12 preferred Sali-Synt to placebo in helping xerostomia.

• Authors: K Kaarela, O Mutru
• Journal: Scandinavian journal of rheumatology (Scand J Rheumatol) Vol. 11 Issue 1 Pg. 39-40 ( 1982) ISSN: 0300-9742 [Print] England
• PMID: 7038859 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Sali-synt
• Solutions

Topics

• Adult
• Aged
• Clinical Trials as Topic
• Double-Blind Method
• Female
• Humans
• Middle Aged
• Saliva
• Sjogren's Syndrome (complications)
• Solutions (therapeutic use)
• Xerostomia (drug therapy, etiology)