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Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis.

Abstract
The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls. There was significant hyperinsulinemia in the DISH group, most marked at 2 h after the glucose challenge. Growth hormone levels were found to be normal in each group. The marked hyperinsulinemia in patients with DISH may play a role in the pathogenesis of this condition.
AuthorsG O Littlejohn, H A Smythe
JournalThe Journal of rheumatology (J Rheumatol) 1981 Nov-Dec Vol. 8 Issue 6 Pg. 965-8 ISSN: 0315-162X [Print] Canada
PMID7035664 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Insulin
Topics
  • Aged
  • Bone Diseases (blood)
  • Glucose Tolerance Test
  • Humans
  • Insulin (blood)
  • Male
  • Middle Aged

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