Kidney transplantation in uremic children with cystinosis.

Abstract

10 children underwent cadaveric renal transplantation between the ages of 8.0 and 12.5 years for uremia secondary to infantile cystinosis. 6 children are doing well 6-62 months after-transplantation. 3 of the 4 other recipients required a second graft and eventually died of uremia or fulminant viral encephalitis, the other lost her first graft due to accelerated acute rejection and is now on maintenance hemodialysis. No further systemic complications of cystinosis have been observed in the patients with functioning grafts. Our experience confirms that kidney transplantation is the treatment of choice for uremic children with infantile cystinosis.

• Authors: R P Langlois, S O'Regan, M Pelletier, P Robitaille
• Journal: Nephron (Nephron) Vol. 28 Issue 6 Pg. 273-5 ( 1981) ISSN: 1660-8151 [Print] Switzerland
• PMID: 7031493 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Cadaver
• Child
• Cystinosis (surgery)
• Female
• Follow-Up Studies
• Humans
• Kidney Transplantation
• Male
• Uremia (surgery)