Menstrual regulation with prostaglandin analogues.

Abstract

The development of generally applicable, simple non-surgical methods for menstrual regulation has been desired for a long time. Such an approach to fertility control depends on the availability of a suitable therapeutic agent that should be effective, reliable, simple to administer and free from disturbing side effects. The classical prostaglandins have shown the capability but are unsuitable mainly due to high incidence of side effects. Most of these drawbacks seem to be overcome when prostaglandin analogues are used; however, vaginal administration caused appreciable pain in 10-30% of women, and so severely limits self-administration of these analogues.

• Authors: K Hagenfeldt, M Bygdeman
• Journal: Reproduccion (Reproduccion) 1981 Jul-Sep Vol. 5 Issue 3 Pg. 195-201 ISSN: 0303-5220 [Print] England
• PMID: 7026317 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Abortifacient Agents
• Abortifacient Agents, Nonsteroidal
• Prostaglandins F, Synthetic
• Prostaglandins, Synthetic
• Suppositories
• 16,16-dimethylprostaglandin F2alpha
• Dinoprost

Topics

• Abortifacient Agents (administration & dosage)
• Abortifacient Agents, Nonsteroidal (administration & dosage)
• Abortion, Induced (methods)
• Clinical Trials as Topic
• Dilatation and Curettage
• Dinoprost (analogs & derivatives)
• Female
• Humans
• Pain (etiology)
• Pregnancy
• Prostaglandins F, Synthetic (administration & dosage, adverse effects)
• Prostaglandins, Synthetic (administration & dosage, adverse effects)
• Self Administration
• Suppositories
• Vacuum Curettage
• Vagina