[Megalocytic interstitial nephritis. A contribution to the differential diagnosis of the large insufficient kidney].

Abstract

After a female patient had presented with advanced renal failure, bilateral enormous increase in kidney size radiologically, urinary tract infection (E. coli) and septicemia, autopsy disclosed megalocytic interstitial nephritis (MIN). Clinical and pathological differentiation from renal parenchymal malakoplakia (RPM) is discussed. A literature survey of 15 cases of MIN and 35 observations of RPM points to certain differences between the two entities, i.e. an increased incidence of bilateral pathology in MIN, mor frequent extrarenal localizations in RPM, absent Michaelis-Gutmann bodies and a predominantly cortical distribution in MIN. The similarities, however, suggest that the two conditions might represent different stages of one and the same disease process.

• Authors: B Zürcher, B Truniger, J Laissue
• Journal: Schweizerische medizinische Wochenschrift (Schweiz Med Wochenschr) Vol. 111 Issue 31-32 Pg. 1153-8 (Aug 04 1981) ISSN: 0036-7672 [Print] Switzerland
• Vernacular Title: Grosszellige interstitielle Nephritis. Ein Beitrag zur Differentialdiagnose der grossen insuffizienten Niere.
• PMID: 7025195 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Diagnosis, Differential
• Escherichia coli Infections (pathology)
• Female
• Humans
• Kidney (pathology)
• Kidney Failure, Chronic (diagnosis, pathology)
• Middle Aged
• Nephritis, Interstitial (diagnosis, pathology)
• Sepsis (pathology)