SearchDictionaryMobileLogin

Prospective clinical trial on the efficacy of amoxycillin administered twice or four times daily in children with respiratory tract infections.

AbstractThirty-four children with upper or lower respiratory tract infections were randomly allocated to receive either a twice daily or four times daily dose of 50 mg amoxycillin/kg body-weight/day. Mean duration of therapy was identical in both groups. Peak and trough antibiotic concentrations were determined. Eradication of bacteria, clinical improvement and side-effects were comparable in both groups.
AuthorsF D Daschner, U Behre, A Dalhoff
JournalThe Journal of international medical research (J Int Med Res) Vol. 9 Issue 4 Pg. 274-6 ( 1981) ISSN: 0300-0605 ENGLAND
PMID7021263 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Amoxicillin
Topics
  • Administration, Oral
  • Amoxicillin (administration & dosage)
  • Bacterial Infections (drug therapy)
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Humans
  • Infant
  • Prospective Studies
  • Random Allocation
  • Respiratory Tract Infections (drug therapy)