Abstract |
Two hundred patients undergoing prostatic surgery at 2 hospitals were randomly allocated into 4 equal groups. The groups were a control, cephalexin, co-trimoxazole and carfecillin treated groups. The incidence of urinary tract infections and other complications of prostatic surgery were studied in each group after a short-term prophylactic regime of 3 doses of the antibiotic. The incidence of urinary infection was significantly improved from 28% in the control group to 8% and 16% in the co-trimoxazole and cephalexin groups respectively. Carfecillin was not effective in reducing urinary infection. However, all 3 antibiotics reduced the incidence of other infective sequelae.
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Authors | P J Shah, G Williams, M Chaudary |
Journal | British journal of urology
(Br J Urol)
Vol. 53
Issue 4
Pg. 339-43
(Aug 1981)
ISSN: 0007-1331 [Print] England |
PMID | 7020820
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Bacterial Agents
- Drug Combinations
- Trimethoprim, Sulfamethoxazole Drug Combination
- Carfecillin
- Trimethoprim
- Sulfamethoxazole
- Cephalexin
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Topics |
- Anti-Bacterial Agents
(therapeutic use)
- Carfecillin
(therapeutic use)
- Cephalexin
(therapeutic use)
- Clinical Trials as Topic
- Drug Combinations
(therapeutic use)
- Humans
- Male
- Postoperative Complications
(prevention & control)
- Premedication
- Prostatectomy
- Sulfamethoxazole
(therapeutic use)
- Trimethoprim
(therapeutic use)
- Trimethoprim, Sulfamethoxazole Drug Combination
- Urinary Tract Infections
(prevention & control)
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