Abstract |
Right and left ventricular outputs, pulmonary and systemic blood flows, and blood flows in both directions through the ductus arteriosus were measured before and during positive-end-expiratory-pressure in 5 premature lambs with induced hyaline membrane disease. During positive-end-expiratory-pressure, right ventricular output increased in all lambs without any significant change in left ventricular output or pulmonary vascular resistance. Left-to-right ductus flow decreased in lambs which initially had large left-to-right ductus shunts. significant right-to-left ductus flow did not occur before or during positive-end-expiratory-pressure.
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Authors | R B Cotton, D P Lindstrom, K S Kanarek, H Sundell, M T Stahlman |
Journal | Acta paediatrica Scandinavica
(Acta Paediatr Scand)
Vol. 69
Issue 5
Pg. 603-6
(Sep 1980)
ISSN: 0001-656X [Print] Sweden |
PMID | 7015782
(Publication Type: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Animals
- Cardiac Output
- Ductus Arteriosus
(physiopathology)
- Hemodynamics
- Humans
- Hyaline Membrane Disease
(physiopathology, therapy)
- Infant, Newborn
- Intermittent Positive-Pressure Ventilation
(methods)
- Positive-Pressure Respiration
(methods)
- Sheep
- Vascular Resistance
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